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Buy marijuana Hamilton have found evidence of brain changes in teens and young adults who smoke marijuana. In 2013, Rocío Martín-Santos, MD, PhD, at the University of Barcelona, and colleagues reviewed 43 studies of chronic cannabis use and the brain. They found consistent evidence of both structural brain abnormalities and altered neural activity in marijuana users. Only eight of those studies focused on adolescents, but the findings from those studies suggested that both structural and functional brain changes emerge soon after adolescents start using the drug. Those changes may still be evident after a month of abstaining from the drug, the researchers reported (PLOS ONE, 2013).

Some of those brain abnormalities have been linked to cognitive differences. Gruber found that regular, heavy marijuana users — those who reported smoking five of the last seven days, and more than 2,500 times in their lives — had damage to their brains’ white matter, which helps enable communication among neurons. Those white matter changes were correlated with higher impulsivity, she found, particularly in people who began smoking before age 16 (Psychopharmacology, 2013).

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